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  7. 5-Fluorouracil, 99%

5-Fluorouracil, 99%

Product Code. 11485523
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Product Code. 11485523 Supplier Thermo Scientific Alfa Aesar Supplier No. A13456.14
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Description

CAS: 51-21-8 | C4H3FN2O2 | 130.08 g/mol

5-Fluorouracil is used as an antitumor agent in the treatment of anal, breast, colorectal, oesophageal, stomach, pancreatic and skin cancers. It finds application as a suicide inhibitor due to its irreversible inhibition of thymidylate synthase. It is also used in the treatment of actinic keratoses and bowen's disease. Further, it serves as a potent antineoplastic agent in clinical use. In addition to this, it acts as a DNA synthesis inhibitor.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in dimethylformamide, dimethyl sulfoxide, methanol, hot water, ammonium hydroxide, sodium hydroxide, ethanol and water.

Notes
Store in a cool place. Incompatible with strong oxidizing agents and strong bases.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 51-21-8
Molecular Formula C4H3FN2O2
Molecular Weight (g/mol) 130.08
MDL Number MFCD00006018
InChI Key GHASVSINZRGABV-UHFFFAOYSA-N
Synonym 5-fluorouracil, fluorouracil, 5-fu, fluoroplex, adrucil, efudex, carac, fluracil, fluoroblastin, kecimeton
PubChem CID 3385
ChEBI CHEBI:46345
IUPAC Name 5-fluoro-1H-pyrimidine-2,4-dione
SMILES FC1=CNC(=O)NC1=O

Specifications

Melting Point ∼282°C (decomposition)
Assay Percent Range 99%
Quantity 25 g
UN Number UN2811
Beilstein 127172
Sensitivity Light sensitive
Merck Index 14,4181
Solubility Information Soluble in dimethylformamide,dimethyl sulfoxide,methanol,hot water,ammonium hydroxide,sodium hydroxide,ethanol and water.
Formula Weight 130.08
Percent Purity 99%
Chemical Name or Material 5-Fluorouracil
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Sicurezza e movimentazione

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Identificativo prodotto
  • 5-Fluorouracil
 Avvertenza
  • Danger
 Categoria di pericolo
  • Acute toxicity Category 3
  • Acute toxicity Category 4
  • Serious eye damage/eye irritation Category 2
  • Germ cell mutagenicity Category 2
  • Reproductive toxicity Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
 Indicazioni di pericolo
  • H301-Toxic if swallowed.
  • H312-Harmful in contact with skin.
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H332-Harmful if inhaled.
  • H335-May cause respiratory irritation.
  • H341-Suspected of causing genetic defects.
  • H361d-Suspected of damaging the unborn child.
 Consigli di prudenza
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P332+P313-If skin irritation occurs: Get medical advice/attention.
  • P337+P313-If eye irritation persists: Get medical advice/attention.
 Informazioni supplementari
  • MIXTURE LIST-Contain: Fluorouracil
SDS

RUO – Research Use Only

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