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Invitrogen™ A2M Polyclonal Antibody
Goat Polyclonal Antibody
Brand: Invitrogen™ PA5143136
This item is not returnable.
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Description
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
Alpha 2-Macroglobulin (a2M), is a approximately 720-kDa homotetrameric glycoprotein composed of four identical approximately 180 kDa subunits. aAlpha 2M shares with other alpha-macroglobulins, like the complement components C3 and C4 and the pregnancy zone protein PZP, an extraordinary binding capacity for a variety of ligands. This allows the alpha-macroglobulins to serve as humoral defense barriers against foreign peptides in the plasma. Alpha 2M interacts and captures virtually any proteinase, often referred to as a panprotease inhibitor. In the brain of Alzheimer's disease (AD) patients, Alpha 2M also has been localized to diffuse amyloid plaques, supporting an important role for alpha 2M in AD etiopathology.
Specifications
| A2M | |
| Polyclonal | |
| Unconjugated | |
| A2M | |
| A2M; A2m1; A2maa; A2MAC1; A2MD; A2mp; Alpha 2 M; Alpha-2-M; Alpha-2-M (A2M); alpha-2-macroglobulin; Alpha-2-macroglobulin-P; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5; CPAMD5; DKFZp779B086; FWP007; LOC100061656; Mam; S863 7; S863-7 | |
| Goat | |
| Ammonium sulfate precipitation | |
| RUO | |
| 2 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 0.5 mg/mL | |
| TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
| P01023 | |
| A2M | |
| Peptide with sequence C-TSLTVRVNYKDRSP (aa 417-430). | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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