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Invitrogen™ Active/Pro-Caspase 3 Recombinant Rabbit Monoclonal Antibody (7T1W5)
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA535333
This item is not returnable.
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Description
Immunogen sequence: SGISLDNSYK MDYPEMGLCI IINNKNFHKS TGMTSRSGTD VDAANLRETF RNLKYEVRNK NDLTREEIVE LMRDVSKEDH SKRSSFVCVL LSHGEEGIIF GTNGPVDLKK ITNFFRGDRC RSLTGKPKLF IIQACRGTEL DCGIETD.
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
Specifications
| Active/Pro-Caspase 3 | |
| Recombinant Monoclonal | |
| 1.14 mg/mL | |
| PBS with 50% glycerol, 0.05% BSA and 0.09% sodium azide; pH 7.3 | |
| P42574, P70677 | |
| CASP3 | |
| Recombinant protein (or fragment). | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
| ELISA, Western Blot | |
| 7T1W5 | |
| Unconjugated | |
| CASP3 | |
| A830040C14Rik; AC-3; Apopain; Casp3; CASP-3; caspase 3; Caspase 3 apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis related cysteine protease; Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis-related cysteine peptidase; caspase 3, apoptosis-related cysteine protease; caspase-3; Caspase-3 subunit p12; Caspase-3 subunit p17; CC3; Cpp32; CPP-32; CPP32B; CPP32beta; cysteine protease CPP32; IRP; Lice; mldy; PARP cleavage protease; procaspase3; protein Yama; SCA-1; SREBP cleavage activity 1; Yama; yama protein | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 12367, 836 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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