missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Cell Culture Media, Supplements, and Reagents
  4. Cell Culture Reagents, Antibiotics and Supplements
  5. Antibiotics
  6. Amphotericin B, Streptomyces nodosus

Amphotericin B, Streptomyces nodosus

Product Code. 15474089
Change view
Click to view available options
Quantity:
100 mg
1 g
5 g
Unit Size:
100mg
1g
5g
3 product options available for selection
Product selection table with 3 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity Unit Size
15474089 100 mg 100mg
15454089 1 g 1g
15464089 5 g 5g
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 3 options available.
3 options
This item is not returnable. View return policy
Product Code. 15474089 Supplier Thermo Scientific Alfa Aesar Supplier No. J61491.MC
 Restricted Item
In Stock
Add to basket

missing translation for 'validMainframeMsg'

This item is not returnable. View return policy

Description

Amphotericin B, CAS # 1397-89-3, is an antifungal that has been used against fungus caused by protozoan parasites of Leishmania genus. | CAS: 1397-89-3 | C47H73NO17 | 924.09 g/mol

Amphotericin B, antifungal activity has been used against leishmaniasis caused by protozoan parasites of the Leishmania genus. Amphotericin B trihydrate was observed to cause suppression of bone marrow progenitor cells and to induce Actinomycin D(CR001) sensitivity in drug resistant HELA cells in vitro.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Amphotericin B is an antibiotic that has antifungal activity and is produced mainly by Streptomyces nodosus

Applications

  • It has antifungal activity against fungus caused by protozoan parasites of Leishmania genus by binding to an essential component of the fungal cell membrane and altering cell membrane permeability
  • It can suppress bone marrow progenitor cells and induce Actinomycin D(CR001) sensitivity in drug resistant HELA cells in vitro
TRUSTED_SUSTAINABILITY

Chemische Identifikatoren

CAS 1397-89-3
Molecular Formula C47H73NO17
Molecular Weight (g/mol) 924.09
MDL Number MFCD00877763
InChI Key APKFDSVGJQXUKY-ZNVUZQDLSA-N
PubChem CID 134129663
IUPAC Name (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19Z,21Z,23Z,25Z,27Z,29Z,31Z,33R,35S,36R,37S)-33-{[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy}-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid
SMILES C[C@H]1O[C@@H](O[C@@H]2C[C@@H]3O[C@@](O)(C[C@H](O)[C@H]3C(O)=O)C[C@@H](O)C[C@@H](O)[C@H](O)CC[C@@H](O)C[C@@H](O)CC(=O)O[C@@H](C)[C@H](C)[C@H](O)[C@@H](C)\C=C/C=C\C=C/C=C\C=C/C=C\C=C/2)[C@@H](O)[C@@H](N)[C@@H]1O

Spezifikation

Type Amphotericin B
Physical Form Powder
Color Yellow
Quantity 100 mg
Sensitivity Light and moisture sensitive
Beilstein 78342
Merck Index 14,585
Solubility Information Soluble in aqueous buffers at pH 2;0 or 11;0; Insoluble at pH 6;0-7;0; Also soluble in DMSO or DMF
Formula Weight 924.1
Chemical Name or Material Amphotericin B, Streptomyces nodosus

Sicherheit und Handhabung

compliance-icons
Produktidentifikator
  • Amphotericin B, Streptomyces nodosus
 Signalwort
  • Warning
 Gefahrenkategorie
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
 Gefahrenhinweis
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
 Sicherheitshinweis
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
 Ergänzende Informationen
  • MIXTURE LIST-Contain: Amphotericin B
Sicherheitsdatenblatt (SDS)

RUO – Research Use Only

Name des Produkts
Wählen Sie ein Thema

Indem Sie auf Absenden klicken, erklären Sie sich damit einverstanden, dass Fisher Scientific sich mit Ihnen in Verbindung setzen kann, um Ihr Feedback in diesem Formular zu bearbeiten. Wir werden Ihre Informationen nicht für andere Zwecke weitergeben. Alle bereitgestellten Kontaktinformationen werden in Übereinstimmung mit unserer Datenschutzrichtlinie aufbewahrt. Datenschutzrichtlinie.