missing translation for 'onlineSavingsMsg'
Learn More
Learn More
AMPK beta 1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 10308-1-AP-150UL
This item is not returnable.
View return policy
Description
AMPK beta 1 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.Specifications
| AMPK beta 1 | |
| Polyclonal | |
| Unconjugated | |
| PRKAB1 | |
| AMPK, AMPK beta 1, AMPK subunit beta 1, AMPKb, HAMPKb, PRKAB1 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 19079, 5564 | |
| -20°C | |
| Liquid |
| Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| 0.23 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| Q9R078, Q9Y478 | |
| Prkab1 | |
| AMPK beta 1 Fusion Protein Ag0301 | |
| 150 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction