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CD18 (Integrin β2 chain, CR3/CR4) Mouse anti-Human, FITC, Clone: L130, BD
Mouse Monoclonal Antibody
Brand: BD Biosciences 347953
Description
CD18 (Anti-LFA-1β), clone L130, is derived from hybridization of mouse Sp2/0 myeloma cells with spleen cells from BALB/c mice immunized with thymic T-cell antigen receptor (TCR)-γ/δ+ T lymphocytes.
CD18 (Anti-LFA-1β) recognizes the Mr 95-kdalton (kDa) β chain of the leucocyte function–associated antigen-1 (LFA-1). LFA-1, a member of a subfamily of integrin receptors, is a leucocyte adhesion receptor that binds to an intercellular adhesion molecule (ICAM) on target tissues. This subfamily consists of three heterodimeric proteins that share a common noncovalently-associated β chain (CD18 antigen) but possess distinct α-subunits recognized by CD11a (anti-LFA-1α), CD11b (Leu-15), and CD11c (Leu-M5).
Specifications
| CD18 | |
| Monoclonal | |
| 6.25μg/mL | |
| Phosphate buffered saline with gelatin and 0.1% sodium azide. | |
| 100 Tests | |
| Immunology | |
| Human | |
| Purified |
| Flow Cytometry | |
| L130 | |
| FITC | |
| Mouse | |
| RUO | |
| Primary | |
| Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed. | |
| IgG1 κ |
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