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CD25 Mouse anti-Human, PE-Cy7, Clone: M-A251, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 557741

Additional Details : Weight : 0.50000kg

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Product Code. 15136364

  • 454.00€ / Each


Estimated Shipment
03-05-2021
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Description

Description

The M-A251 monoclonal antibody specifically binds to the 55 kDa type I transmembrane glycoprotein known as the low-affinity interleukin-2 receptor alpha chain subunit (IL-2Rα). CD25 is expressed on regulatory T cells and on activated lymphocytes (T and B) and monocytes. It associates with the IL-2Rβ/CD122 and the IL-2Rγ/CD132 receptor chains to form the high-affinity IL-2R complex. CD25 expression on T and B lymphocytes is upregulated by antigenic or mitogenic stimulation. Soluble CD25/IL-2Rα is produced as a consequence of lymphocyte stimulation and is found in biological fluids following inflammatory responses.

Specifications

Specifications

CD25
M-A251
IL-2R; IL2RA; IL-2Rα; TCGFR; TAC antigen; p55
Affinity Purified
IgG1, κ
RUO
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
PE-Cyanine7
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Murine
100 Tests
Immunology
Primary
Human
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