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CD4 Mouse anti-Human, PE-CF594, Clone: RPA-T4, BD
Mouse Monoclonal Antibody
211.05€ - 429.07€
Specifications
| Antigen | CD4 |
|---|---|
| Clone | RPA-T4 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Conjugate | PE-CF594 |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
15881809
|
BD Biosciences
562316 |
25 Tests |
 212.00€ 211.05€ / Each Save 0.95€ 0.45% Off |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
|
15831779
|
BD Biosciences
562281 |
100 Tests |
431.00€ 429.07€ / Each Save 1.93€ 0.45% Off |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
The RPA-T4 monoclonal antibody specifically binds to CD4, a 59 kDa single-chain transmembrane glycoprotein that is expressed on T-helper/inducer cell populations. CD4 is also expressed on thymocytes subsets and at lower levels on monocytes and macrophages. CD4 functions as a co-receptor in MHC class II-restricted antigen-induced T cell activation and as a receptor for human immunodeficiency viruses (HIV). This antibody binds to the D1 domain (CDR1 and CDR3 epitopes) of the CD4 antigen and reacts with approximately 80% of thymocytes and 45% of peripheral blood lymphocytes. RPA-T4 is capable of blocking HIV-1, gp120, and inhibits syncytium formation.
This antibody is conjugated to BD Horizon™ PE-CF594, which has been developed exclusively by BD Biosciences as a better alternative to PE-Texas Red. PE-CF594 excites and emits at similar wavelengths to PE-Texas Red yet exhibits improved brightness and spectral characteristics. Due to PE having maximal absorption peaks at 496nm and 564nm, PE-CF594 can be excited by the blue (488-nm), green (532-nm) and yellow-green (561-nm) lasers and can be detected with the same filter set as PE-Texas Red (eg 610/20-nm filter).
Specifications
| CD4 | |
| Flow Cytometry | |
| PE-CF594 | |
| RUO | |
| Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| RPA-T4 | |
| Monoclonal | |
| Mouse | |
| Human | |
| IgG1 κ | |
| Affinity Purified | |
| L3T4; T-cell surface antigen T4/Leu-3; W3/25; CD4 antigen (p55) |
For Research Use Only.
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