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CD86 Mouse anti-Human, V450, Clone: 2331 (FUN-1), BD
Mouse Monoclonal Antibody
Brand: BD Biosciences 560357
This item is not returnable.
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Description
2331 (FUN-1) recognizes a 75kDa cell surface protein, CD86 (B70/B7-2), expressed primarily on monocytes and activated B cells. Competitive binding assays demonstrate that, while both 2331 (FUN-1) and IT2.2 (anti-CD86, Mfr. No. 555663) recognize the same molecule, they react with different epitopes. CD86 is the second ligand for CD28 and CTLA-4 and may play an important role in co-stimulation of T cells in primary immune response. 2331 (FUN-1) blocks costimulation activity of CD86 in functional studies. The antibody is conjugated to BD Horizon™ V450, which has been developed for use in multicolor flow cytometry experiments and is available exclusively from BD Biosciences. It is excited by the Violet laser Ex max of 406nm and has an Em Max at 450nm. Conjugates with BD Horizon™ V450 can be used in place of Pacific Blue™ conjugates.
Host Species: Mouse
Clone: 2331(FUN-1)
Isotype: IgG1 κ
Species Reactivity: Human
Flow Cytometry
Specifications
| CD86 | |
| Monoclonal | |
| Violet Fluor 450 (V450) | |
| Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide. | |
| Human HBL-1 Cell Line | |
| 120 Tests | |
| Immunology | |
| Human | |
| IgG1 κ |
| Flow Cytometry | |
| 2331 (FUN-1) | |
| B7.2; B7-2; B-lymphocyte activation antigen B7-2; B70; BU63; CD28LG2; LAB72 | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
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