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PDX-1 Mouse, PE, Clone: 658A5, BD
Mouse Monoclonal Antibody
Brand: BD Biosciences 562161
This item is not returnable.
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Description
The 658A5 monoclonal antibody binds PDX-1 or Pancreas/Duodenum Homeobox Protein-1 encoded by the PDX1 or IPF1 (Insulin Promoter Factor 1) gene. PDX-1 is a key regulator of pancreatic development and adult beta-cell function. Loss of PDX1 gene function in mice and humans results in pancreatic agenesis. PDX-1 is also involved in endocrine precursor cell development by binding the DNA-binding transcription factor Neurogenin-3. PDX-1-positive cells have been obtained by the directed differentiation of human embryonic stem cells through a definitive endoderm lineage.
Specifications
| PDX-1 | |
| Monoclonal | |
| PE | |
| Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
| Human PDX-1 Recombinant Protein | |
| 50 Tests | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| Flow Cytometry | |
| 658A5 | |
| PDX1, GSF, IPF-1, IPF1, IUF-1, IDX-1, STF-1 | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Human, Mouse | |
| IgG1 κ |
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