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  5. Tocris Bioscience™ Apoptosis Activator 2

Tocris Bioscience™ Apoptosis Activator 2
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Product Code. 18025102
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
Product Code. Quantity unitSize
18025102 10 mg 10mg
18044832 50 mg 50mg
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Product Code. 18025102

Brand: Tocris Bioscience™ 2098/10

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This item is not returnable. View return policy

Description

Promotes apoptosome formation and activates caspase-9/caspase-3 pathway. Selectively induces tumor cell apoptosis

Apoptosis activator; promotes the cytochrome c-dependent oligomerization of Apaf-1 into the mature apoptosome. Increases procaspase-9 processing and subsequent caspase-3 activation. Induces apoptosis in tumor cells (IC50 = 4 - 9 μM for leukemia cells) with weak or no effect on normal cell lines or those defective/deficient in Apaf-1, caspase-9 or caspase-3 activity (IC50 > 40 μM).
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 79183-19-0
Molecular Formula C15H9Cl2NO2

Specifications

Quantity 10 mg
Formula Weight 306.14
Purity >99%
Molecular Weight (g/mol) 306.14
Chemical Name or Material Apoptosis Activator 2
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