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Arginase I Mouse, Unlabeled, Clone: 19, BD
Mouse Monoclonal Antibody
222.84€ - 330.63€
Specifications
| Antigen | Arginase I |
|---|---|
| Clone | 19 |
| Concentration | 250μg/mL |
| Applications | Western Blot |
| Classification | Monoclonal |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
15855599
|
BD Biosciences
610708 |
50 μg |
 227.00€ 222.84€ / 1 set Save 4.16€ 1% Off |
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|
15865599
|
BD Biosciences
610709 |
150 μg |
332.00€ 330.63€ / 1 set Save 1.37€ 0.41% Off |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Arginase converts arginine into urea plus ornithine, the final step in urea synthesis. Two different isoforms (I&II) have been isolated with approximately 60% homology at the nucleotide level. While type II is present in many tissues, Arginase I is expressed exclusively in liver. In cultured macrophages, as well as in vivo, Arginase I is induced with nitric oxide synthase (NOS) and the arginase I transactivator C/EBPβ in response to lipopolysaccharide. This response occurs in a dose and time-dependent manner. While the mRNA for NOS appears as early as 2h after treatment, mRNA levels for arginase I peak after twelve hours of lipopolysaccharide treatment. Since the synthesis of nitric oxide by NOS requires arginine, the delayed induction of arginase I may be necessary for the regulation of NOS activity.
Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting
Specifications
| Arginase I | |
| 250μg/mL | |
| Monoclonal | |
| Mouse | |
| Cell Biology | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| IgG1 | |
| Affinity Purified |
| 19 | |
| Western Blot | |
| Unconjugated | |
| RUO | |
| Drosophila, Mouse, Rat | |
| Human Arginase I aa. 53-207 | |
| Primary | |
| Store undiluted at -20°C. |
For Research Use Only.
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