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Invitrogen™ ARPP19 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5103696
This item is not returnable.
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Description
Antibody detects endogenous levels of total ARPP19.
Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. May indirectly enhance GAP-43 expression by binding to the NGF-regulatory region of its mRNA.
Specifications
| ARPP19 | |
| Polyclonal | |
| Unconjugated | |
| ARPP19 | |
| 19kDa; 2700024H10Rik; Arpp12; ARPP16; ARPP-16; Arpp19; ARPP-19; AW559096; cAMP regulated phosphoprotein 19; cAMP regulated phosphoprotein 19kDa; cAMP-regulated phosphoprotein 19; cAMP-regulated phosphoprotein 19kDa; cAMP-regulated phosphoprotein ARPP-19; cAMP-regulated phosphoprotein, 19kDa; cyclic AMP phosphoprotein, 19 kD; cyclic AMP phosphoprotein, 19 kDa; cyclic AMP phosphoprotein, 19kD; ENSAL | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 10776, 59046, 60336 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P56211, P56212, Q712U5 | |
| ARPP19 | |
| A synthesized peptide derived from human ARPP19(Accession P56211), corresponding to amino acid residues M1-K42. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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