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Tocris Bioscience™ Azidothymidine
Description
Selective reverse transcriptase inhibitor. Exhibits 100-fold selectivity for HIV reverse transcriptase over DNA polymerase α. Suppresses HIV-1 replication and enhances cell viability in HIV-1 infected T cells. Attenuates growth of multiple myeloma (MM) cells in vitro and reduces growth of MM tumor xenografts in mice. Increases differentiation iPSCs into cortical neurons and reduces the over-proliferation of neural precursors. Orally bioavailable and brain penetrant. Antiretroviral agent. Also decreases CRISPR-mediated homology directed repair (HDR) efficiency.
Specifications
Specifications
| Purity | 99% |
| Molecular Formula | 3 '-Azido-3 '-deoxythymidine |
| CAS | 30516-87-1 |
| Content And Storage | -20°C |
| Quantity | 50 mg |
| Product Type | Azidothymidine |
| Molecular Weight (g/mol) | M.W. (Observed): 267.24 |
| Inhibitors | Azidothymidine |
For Research Use Only
Product Title
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