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BCAR3 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA534425

Additional Details : Weight : 0.01000kg

Product Code. 15375351

  • 473.00€ / 100µg
Estimated Shipment: 14-05-2024
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Description

Description

A suggested positive control is Hela cell lysate. PA5-34425 can be used with blocking peptide PEP-1467.

Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48.
Specifications

Specifications

BCAR3
Polyclonal
Unconjugated
BCAR3
AI131758; And34; AND-34; Bcar3; breast cancer anti-estrogen resistance 3; breast cancer antiestrogen resistance 3 protein; breast cancer anti-estrogen resistance protein 3; dJ1033H22.2 (breast cancer anti-estrogen resistance 3); KIAA0554; novel SH2-containing protein 2; NSP2; OTTHUMP00000011961; p130Cas-binding protein AND-34; SH2 domain-containing protein 3B; SH2D3B; UNQ271/PRO308
Rabbit
Antigen affinity chromatography
RUO
29815, 310838, 8412
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Liquid
Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
O75815, Q9QZK2
BCAR3
A 16 amino acid synthetic peptide near the amino terminus of human BCAR3
100 μg
Primary
Human, Mouse, Rat
Antibody
IgG
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