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Invitrogen™ BMP-2 Recombinant Rabbit Monoclonal Antibody (3Q0C7)
GREENER_CHOICE

Rabbit Recombinant Monoclonal Antibody

176.00€ - 436.00€

Specifications

Antigen BMP-2
Clone 3Q0C7
Concentration 2.2 mg/mL
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Applications ELISA, Western Blot
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
30283040
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Invitrogen™
MA557903
20 μL
176.00€
20µL
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30282466
GREENER_CHOICE
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Invitrogen™
MA557904
100 μL
436.00€
100µL
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Description

Description

Immunogen sequence: MVAGTRCLLA LLLPQVLLGG AAGLVPELGR RKFAAASSGR PSSQPSDEVL SEFELRLLSM FGLKQRPTPS RDAVVPPYML DLYRRHSGQP GSPAPDHRLE.

Bone Morphogenic Proteins (BMP) are members of the TGF-beta superfamily that affect bone and cartilage formation (Hogan 1996, Reddi 1998 and Francis-West et al. 1999). Mature BMPs are 30-38 kDa proteins that assume a TGF-beta -like cysteine knot configuration. Lovostatin increases bone formation by turning on the bmp-2 gene (Mundy et al. 1999). BMPs stimulate the production of specific bone matrix proteins and alter stromal cell and osteoclast proliferation (Macias et al. 1999, Lecanda et al. 1997). BMPs may also be an important factor for development of the viscera, with roles in cell proliferation, apoptosis, differentiation, and morphogenesis (Hogan 1996, Dale and Wardle 1999). BMPs appear to be responsible for normal dorsal/ventral patterning. Like TGF-beta, BMPs bind to a type II receptor, which then recruits the transducing type I receptor unit, activating the Smad protein signaling pathway (Massague 1994, Derynck 1997, Attisano 1993).
Specifications

Specifications

BMP-2
2.2 mg/mL
ELISA, Western Blot
Unconjugated
Rabbit
RUO
PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3
P12643
650
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human BMP2 (NP_001191.1).
Antibody
3Q0C7
-20°C, Avoid Freeze/Thaw Cycles
Recombinant Monoclonal
Liquid
IgG
Human
BMP2
2610024H22Rik; AI467020; AL117858; AW546137; BB189135; BDA2; BMP; BMP2; BMP-2; BMP2A; BMP-2A; BMPRII; BMPR-II; Bone morphogenetic; Bone morphogenetic protein; Bone morphogenetic protein 2; bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A); bone morphogenetic protein 2A; H-BMP-2; morphogen
BMP2
Primary
Protein A
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