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BRD7 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 51009-2-AP-150UL
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Description
BRD7 acts both as coactivator and as corepressor. For example, it activates the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. In addition, it is required for TP53-mediated cell-cycle arrest in response to oncogene activation. BRD7 promotes acetylation of TP53 at Lys-382, and thereby promotes efficient recruitment of TP53 to target promoters, inhibiting cell cycle progression from G1 to S phase.Specifications
| BRD7 | |
| Polyclonal | |
| Unconjugated | |
| BRD7 | |
| 75 kDa bromodomain protein, BP75, BRD7, bromodomain containing 7, CELTIX1, NAG4, Protein CELTIX 1 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 26992, 29117, 361374 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 0.13 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| O88665, Q9NPI1 | |
| BRD7 | |
| BRD7 Fusion Protein Ag3911 | |
| 150 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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