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Invitrogen™ C-Peptide Monoclonal Antibody (C-PEP-01)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA119159
This item is not returnable.
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Description
This antibody reacts specifically with C-peptide, a part of the proinsulin molecule. Proinsulin consists of three parts: C-peptide and two long strands of amino acids (alpha and beta chains; later become linked together to form the insulin molecule). No cross-reactivity with insulin or other peptide hormones or proteins was observed.
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified.
Specifications
| C-Peptide | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 15mM sodium azide; pH 7.4 | |
| P01308 | |
| INS | |
| Human C-peptide conjugated to BSA. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| ELISA, Immunohistochemistry (Paraffin), Radioimmune Assays (RIA), Immunocytochemistry | |
| C-PEP-01 | |
| Unconjugated | |
| INS | |
| Cpeptide; IDDM; IDDM1; IDDM2; ILPR; INS; Ins1; Ins-1; Ins2-rs1; insulin; insulin 1; Insulin A chain; Insulin B chain; insulin I; insulin-1; Insulin-1 A chain; Insulin-1 B chain; IRDN; MODY10; preproinsulin; proinsulin | |
| Mouse | |
| Protein A | |
| RUO | |
| 3630 | |
| 4°C, do not freeze | |
| Liquid |
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