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C1orf96 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Thermo Scientific PA560366
Additional Details : Weight : 0.02000kg
Description
Immunogen sequence: EEQDAEAGDA EAEDAEDAAL PALPVKDVED KPEQQTRTRE TDKSPTSTEP RQQPSALFAR GNRKAVKSPQ RSSSKIKENK HPFALYGW Highest antigen sequence identity to the following orthologs: Mouse - 63%, Rat - 63%.
Plays a role in microtubule (MT) stabilization and this stabilization involves the maintenance of NUMA1 at the spindle poles. Colocalizes with polyglutamylated MTs to promote MT stabilization and regulate bipolar spindle formation in mitosis. Binding of CCSAP to centrosomes and the spindle around centrosomes during mitosis inhibits MT depolymerization, thereby stabilizing the mitotic spindle (PubMed:26562023). May play a role in embryonic development. May be required for proper cilia beating. [UniProt]Specifications
| C1orf96 | |
| Polyclonal | |
| Unconjugated | |
| CCSAP | |
| 1700054N08Rik; AI853424; C1orf96; C4H1orf96; Ccsap; centriole and spindle-associated protein; centriole, cilia and spindle associated protein; centriole, cilia and spindle-associated protein; CSAP; RGD1563235 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 126731 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry | |
| 0.2 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q6IQ19 | |
| CCSAP | |
| Recombinant protein corresponding to Human C1orf96 | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
Research Use Only