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Invitrogen™ CCR7 Recombinant Rabbit Monoclonal Antibody (HL3075)
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Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA556633

Product Code. 30275392

  • 500.00€ / 100µL

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Description

Description

CCR7 Recombinant Monoclonal Antibody for IHC (P)

CCR7 is a member of the G-protein-coupled chemokine receptor family with seven membrane-spanning domains and functions as a receptor for 6Ckine/SLC (secondary lymphoid-tissue chemokine), CCL19 and CCL21. CCR7 has been shown to be internalized via clathrin-coated pits and the majority recycled back to the plasma membrane. CCR7 is expressed on T cells and can be used to distinguish populations of naive from central and effector memory T cells. CCR7 has been shown to play a role in migration of memory T cells to inflamed tissue. Expression of CCR7 is also found on DC's. During DC maturation CCR7 expression increases and is thought to be involved in a variety of functions: chemotaxis to the lymph node, cellular architecture, rate of endocytosis, survival and maturation.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CCR7
Recombinant Monoclonal
1 mg/mL
PBS with no preservative
BLR2; Bukitt's lymphoma receptor 2; CC chemokine receptor 7; C-C chemokine receptor type 7; C-C CKR-7; C-C motif chemokine receptor 7; CC-CKR-7; CCR7; CCR-7; CD197; CDw197; chemokine (C-C motif) receptor 7; chemokine (C-C) receptor 7; Cmkbr7; EBI1; Ebi1h; EBV-induced G protein-coupled receptor 1; EBV-induced G-protein coupled receptor 1; Epstein-Barr virus induced gene 1; Epstein-Barr virus-induced G-protein coupled receptor 1; EVI1; lymphocyte-specific G protein-coupled peptide receptor; MIP-3 beta receptor
Rabbit
Protein A
RUO
287673
-20°C, Avoid Freeze/Thaw Cycles
Liquid
Immunohistochemistry (Paraffin)
HL3075
Unconjugated
Ccr7
Ccr7
Synthetic peptide encompassing a sequence within the Extracellular domain of human CCR7. The exact sequence is proprietary.
100 μL
Primary
Rat
Antibody
IgG
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