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CD106 (VCAM-1) Monoclonal Antibody (429), Functional Grade, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Brand:  Invitrogen 16-1061-38

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Product Code. 17141112

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Description

Description

The 429 MAb reacts with mouse CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110 kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and upregulate it upon cytokine stimulation. CD106 binds to integrin alpha4beta1 (VLA-4, CD49d/CD29) and Integrin a4b7 (LPAM-1) and these interactions in the bone marrow and thymus are important for early lymphocyte and myeloid development. Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response.

CD106 (VCAM-1) Monoclonal antibody specifically detects CD106 (VCAM-1) in Mouse samples. It is validated for Flow Cytometry, Functional Assay, Neutralization
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD106 (VCAM-1)
Monoclonal
1 mg/mL
PBS with no preservative; pH 7.2
P29533
Rat
5 mg
Primary
Mouse
Antibody
IgG2a κ
Flow Cytometry, Functional Assay, Neutralization
429
Functional Grade
VCAM1
adhesion molecule VCAM-1; CD106; CD106 antigen; DKFZp779G2333; INCAM100; INCAM-100; MGC99561; sCD106; soluble CD106; soluble VCAM 1; sVCAM 1; vascular cell adhesion molecule; vascular cell adhesion molecule 1; vascular cell adhesion molecule-1; vascular cell adhesion protein 1; V-CAM 1; VCAM1; Vcam-1; VCAM1B
Affinity chromatography
RUO
22329
4° C
Liquid
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