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CD11b Mouse, anti-Human, FITC, Clone: ICRF44, STEMCELL Technologies

Mouse Monoclonal Antibody

193.05€ - 410.40€

Specifications

Antigen CD11b
Clone ICRF44
Applications Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence
Classification Monoclonal
Conjugate FITC
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
17188721
Encompass_Preferred
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Stemcell Technologies
60040FI.1
25 Tests
193.05€
25 tests
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17178721
Encompass_Preferred
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Stemcell Technologies
60040FI
100 Tests
410.40€
100 tests
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»
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Description

Description

  • The ICRF44 antibody reacts with an extracellular epitope on CD11b (integrin αM), an ∼170 kDa type 1 transmembrane glycoprotein which associates non-covalently with CD18 to form the heterodimeric Mac-1 receptor
  • Through its interactions with ligands such as ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, heparin, and fibrinogen, Mac-1 influences several processes, including the adherence of neutrophils and monocytes to stimulated endothelium, and phagocytosis of complement-coated particles
  • CD11b is expressed on the surface of granulocytes, monocytes, NK cells, dendritic cells, tissue macrophages, and subsets of T and B cells, and has been used as a marker to distinguish naive and memory CD8+ T cells
  • This antibody clone has been verified for purity assessments of cells isolated with EasySep™ kits, including EasySep™ Human Monocyte Enrichment Kit (Catalog #19059), and for labeling human mesenchymal cells grown in MesenCult™ Proliferation Kit (Human; Catalog #05411)
Specifications

Specifications

CD11b
Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence
FITC
Baboon, Cynomolgus, Rhesus Monkey, Chimpanzee, Human
Primary
ICRF44
Monoclonal
Mouse
IgG1 κ
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