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CD132 Monoclonal Antibody (TUGh4), Biotin, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 13-1329-80
Additional Details : Weight : 0.25000kg
Description
Description: This TUGh4 monoclonal antibody reacts with human CD132, the common gamma chain (gamma c) shared by the IL-2, IL-4, IL-7, IL-9, and IL-15 receptors. This approximately 65 kDa receptor component is expressed on T and B lymphocytes, NK cells, monocytes, and granulocytes. CD132 is involved in intracellular signal transduction by associating with effector molecules within the cytoplasm. Mutations in the human gamma chain gene result in X-linked severe combined immunodeficiency (XSCID), a disease characterized by T cell deficiency leading to impairment of cell-mediated and humoral immunity. Applications Reported: This antibody has been reported for use in flow cytometric analysis. Applications Tested: This TUGh4 antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 0.125 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Filtration: 0.2 μm post-manufacturing filtered.
IL2RG is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.Specifications
| CD132 | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2 | |
| P31785 | |
| IL2RG | |
| Affinity chromatography | |
| RUO | |
| 3561 | |
| 4° C, store in dark, DO NOT FREEZE! | |
| Liquid |
| Flow Cytometry | |
| TUGh4 | |
| Biotin | |
| IL2RG | |
| IL2RG, CIDX, IL-2RG, IMD4, P64, SCIDX, SCIDX1, CD132 antigen, IL-2 receptor subunit gamma, IL-2R subunit gamma, cytokine receptor common subunit gamma, gamma (c), gammaC, interleukin-2 receptor subunit gamma, IL2R gamma | |
| Rat | |
| 25 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG2b λ |
For Research Use Only.