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CD18 Rat anti-Mouse, BB700, Clone: C71/16, BD Optibuild™
Description
The C71/16 monoclonal antibody specifically binds to mouse CD18 which is also known as the common β2 chain of LFA-1 (CD11a/CD18, αLβ2 integrin), Mac-1 (CD11b/CD18, αMβ2 integrin), and gp150, 95 (CD11c/CD18, αxβ2 integrin). CD18 is a type I transmembrane glycoprotein. Expression of CD18 is limited to leukocytes, where it is widely distributed in consort with the three integrin α chains (CD11a, CD11b, and CD11c). Among splenocytes, NK cells have the highest density of CD18, and T lymphocytes express a higher density than the remaining cells. The β2 integrins are important mediators of leukocyte-endothelium interactions.
Specifications
Specifications
| Antigen | CD18 |
| Classification | Monoclonal |
| Clone | C71/16 |
| Concentration | 0.2mg/mL |
| Conjugate | Brilliant Blue 700 (BB700) |
| Formulation | Aqueous buffered solution containing ≤0.09% sodium azide. |
| Gene Alias | Itgb2, Integrin beta-2, ITB2, LAD, LCAMB, LFA-1/Mac-1/p150,95 subunit beta |
| Host Species | Rat |
| Immunogen | Cell membrane glycoproteins from mouse T-cell lymphoma BW5147 |
| Purification Method | Affinity Purified |
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