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  6. CD235ab (Glycophorin A/B) Mouse, anti-Human, APC, Clone: HIR2 (GA-R2), STEMCELL Technologies

CD235ab (Glycophorin A/B) Mouse, anti-Human, APC, Clone: HIR2 (GA-R2), STEMCELL Technologies

Mouse Monoclonal Antibody

POA - 589.95€

Specifications

Antigen CD235ab (Glycophorin A/B)
Clone HIR2 (GA-R2)
Applications Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence
Classification Monoclonal
Conjugate APC
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17149101
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Stemcell Technologies
60111AZ.1 		25 μg This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Technical Support team on 056 260 260 for assistance.
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17139101
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Stemcell Technologies
60111AZ 		100 μg
589.95€
100µg
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Description

Description

  • The HIR2 (GA-R2) antibody recognizes an epitope common to the N-terminal region of human CD235a (glycophorin A) and CD235b (glycophorin B), homologous type I sialoglycoproteins of the erythrocyte (red blood cell) membrane that bear the antigenic determinants for the MN and Ss blood groups
  • CD235ab is expressed on early- and late-stage erythroblasts, mature erythrocytes, and erythroid cell lines such as K562 and HEL, but not on other cell types
  • CD235a is abundantly expressed whereas CD235b is a relatively minor membrane component
  • The proteins are believed to provide a large mucin-like surface to erythrocytes that acts to minimize aggregation in the circulation
  • The HIR2 antibody binds with higher affinity to CD235a than CD235b, and agglutinates untreated erythrocytes
Specifications

Specifications

CD235ab (Glycophorin A/B)
Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence
APC
Human
Primary
HIR2 (GA-R2)
Monoclonal
Mouse
IgG2b κ
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