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CD24 Rat, anti-Mouse, PE, Clone: M1/69, STEMCELL Technologies
Rat Monoclonal Antibody
Brand: Stemcell Technologies 60099PE
This item is not returnable.
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Description
- The M1/69 antibody reacts with murine CD24, an ∼35 - 45 kDa glycoprotein expressed on lymphocytes, granulocytes, thymocytes, erythrocytes, epithelial cells, neurons, and dendritic cells
- CD24 is differentially expressed during T and B cell development, and is not found on the majority of mature peripheral T cells or plasma cells
- It is expressed on pro-B, pre-B and mature B cells, but expression is strongly down-regulated after B cell activation
- CD24 is involved in regulating B cell apoptosis and in preventing terminal differentiation of B cells into antibody-secreting plasmablasts and plasma cells
- It acts as an adhesion or co-stimulatory molecule and is involved in lymphocyte activation, proliferation and differentiation through homophilic interactions or by binding to ligands such as P-selectin (CD62P)
Specifications
| CD24 | |
| Monoclonal | |
| PE | |
| 200 μg | |
| Mouse | |
| B Cells, Mammary Cells |
| Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence | |
| M1/69 | |
| Rat | |
| Primary | |
| IgG2b κ |
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