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CD3 Mouse anti-Rat, FITC, Clone: G4.18, BD

Mouse Monoclonal Antibody

143.81€ - 505.01€

Specifications

Antigen CD3
Clone G4.18
Concentration 0.5mg/mL
Applications Flow Cytometry
Classification Monoclonal
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Products 2
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Product Code Brand Quantity Price Quantity & Availability  
15839848
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BD Biosciences
559975
0.1 mg
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145.00€
143.81€ / Each
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15817878
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BD Biosciences
554832
0.5 mg
ONLINE EXCLUSIVE PRICE
510.00€
505.01€ / Each
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Description

Description

The G4.18 antibody reacts with the T-cell receptor-associated CD3 cell-surface antigen found on thymocytes, peripheral T lymphocytes, and dendritic epidermal T cells. It has been reported that CD3 expression is down-regulated within 24 hours in concanavalin A-stimulated rat T cells, and soluble mAb inhibits the allogeneic mixed-lymphocyte proliferative response and cell-mediated cytotoxicity to allogeneic target cells. In vivo treatment with G4.18 mAb prevents cardiac and skin allograft rejection, resulting in donor-specific tolerance. Pre-incubation of splenocytes with the alternate anti-rat CD3 monoclonal antibody, 1F4 (Cat. No. 556970), blocks staining with mAb G4.18.

This antibody is routinely tested by flow cyometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Specifications

Specifications

CD3
0.5mg/mL
Monoclonal
Mouse
Rat
PHA-stimulated rat lymph node and spleen cells
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
G4.18
Flow Cytometry
FITC
RUO
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
IgG3 κ
Affinity Purified
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SDS
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Documents

Product Certifications

For Research Use Only.

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