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CD31 (PECAM-1) Monoclonal Antibody (390), NovaFluor™ Red 725, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
195.00€ - 359.00€
Specifications
| Antigen | CD31 (PECAM-1) |
|---|---|
| Clone | 390 |
| Concentration | 0.1 mg/mL |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
Description
CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.Specifications
| CD31 (PECAM-1) | |
| 0.1 mg/mL | |
| Monoclonal | |
| Liquid | |
| RUO | |
| PBS with 0.09% sodium azide; pH 7.2 | |
| C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule | |
| Pecam1 | |
| Primary | |
| 4° C, store in dark, DO NOT FREEZE! |
| 390 | |
| Flow Cytometry | |
| NovaFluor Red 725 | |
| Rat | |
| Mouse | |
| Q08481 | |
| 18613 | |
| IgG2a κ | |
| Affinity chromatography | |
| Pecam1 |
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