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CD41/Integrin alpha 2b Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

145.00€ - 410.00€

Specifications

Antigen CD41/Integrin alpha 2b
Concentration 0.45 mg/mL
Applications Western Blot, Immunohistochemistry (Paraffin), Immunoprecipitation
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16803035
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Proteintech
24552-1-AP-20UL
20 μL
145.00€
20µL
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16893025
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Proteintech
24552-1-AP-150UL
150 μL
410.00€
150µL
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Description

Description

CD41 (platelet glycoprotein IIb, ITGA2B) is composed of two subunits -120 kDa a, alpha and 23 kDa b, beta- that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. CD41 is also involved in blood coagulation by mediating platelet aggregation. Upon blood vessel damage, CD41 binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during the early stages of hematopoietic differentiation. Diseases associated with CD41 dysfunction include Glansmann Thrombasthenia, and Platelet type-16 bleeding disorder.
Specifications

Specifications

CD41/Integrin alpha 2b
Western Blot, Immunohistochemistry (Paraffin), Immunoprecipitation
Unconjugated
Rabbit
Rat, Human, Mouse
P08514, Q9QUM0
16399, 3674, 685269
CD41/Integrin alpha 2b Fusion Protein Ag19459
Primary
-20°C
ITGA2B
0.45 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
CD41, CD41B, GP2B, GPalpha IIb, GPIIb, GTA, HPA3, Integrin alpha IIb, ITGA2B, ITGAB
Itga2b
IgG
Antigen Affinity Chromatography
Antibody
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SDS
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Documents

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