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CD41a Monoclonal Antibody (eBioMWReg30 (MWReg30)), Super Bright™ 600, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
148.00€ - 423.00€
Specifications
| Antigen | CD41a |
|---|---|
| Clone | eBioMWReg30 (MWReg30) |
| Concentration | 0.2 mg/mL |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
Description
The eBioMWReg30 monoclonal antibody reacts with mouse CD41 (fibrinogen receptor, gpIIb, integrin alpha IIb). While initially thought to be expressed exclusively on the surface of platelets and megakaryocytes, it has been demonstrated that CD41 is also exp
CD41 (platelet glycoprotein IIb, ITGA2B) is composed of two subunits -120 kDa a, alpha and 23 kDa b, beta- that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. CD41 is also involved in blood coagulation by mediating platelet aggregation. Upon blood vessel damage, CD41 binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during the early stages of hematopoietic differentiation. Diseases associated with CD41 dysfunction include Glansmann Thrombasthenia, and Platelet type-16 bleeding disorder.Specifications
| CD41a | |
| 0.2 mg/mL | |
| Monoclonal | |
| Liquid | |
| RUO | |
| Q9QUM0 | |
| Itga2b | |
| Primary | |
| Antibody |
| eBioMWReg30 (MWReg30) | |
| Flow Cytometry | |
| Super Bright 600 | |
| Rat | |
| Mouse | |
| 16399 | |
| IgG1 κ | |
| 4° C, store in dark, DO NOT FREEZE! | |
| Itga2b |
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