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CD44 Rat, anti-Mouse, Biotin, Clone: IM7, STEMCELL Technologies
Rat Monoclonal Antibody
Brand: Stemcell Technologies 60068BT
Description
- The IM7 antibody reacts with CD44 (Ly-24), an ∼80 - 95 kDa type 1 transmembrane glycoprotein involved in cell-cell and cell-matrix interactions
- CD44 is expressed on the surface of many cells, including leukocytes and hepatocytes, as well as endothelial, epithelial, and mesenchymal cells
- Expression levels increase upon activation of T and B cells, and memory cells exhibit a CD44 high phenotype
- CD44 binds many ligands, including hyaluronic acid, collagen, fibronectin, growth factors, and metalloproteinases, thus modulating processes such as lymphocyte activation, recirculation and homing, leukocyte rolling and aggregation, hematopoiesis, and tumor metastasis
- This antibody clone has been verified for purity assessments of cells isolated with EasySep™ kits, including EasySep™ Mouse CD4+ T Cell Isolation Kit (Catalog #19852), EasySep™ Mouse CD4+CD62L+ T Cell Isolation Kit (Catalog #18765), and EasySep™ Human Naive CD4+ T Cell Isolation Kit (Catalog #19555)
Specifications
| CD44 | |
| Monoclonal | |
| Biotin | |
| 500 μg | |
| Baboon, Cynomolgus, Rhesus Monkey, Chimpanzee, Human | |
| Mammary Cells, T Cells |
| Immunohistochemistry, ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence | |
| IM7 | |
| Rat | |
| Primary | |
| IgG2b κ |
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