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CD85j (ILT2) Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA529567
Additional Details : Weight : 0.01000kg
Description
Recommended positive controls: 293T, A431, Jurkat, Raji. Predicted reactivity: Human (98%), Rhesus Monkey (83%), Chimpanzee (89%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.Especificaciones
CD85j (ILT2) | |
Polyclonal | |
Unconjugated | |
LILRB1 | |
CD85 antigen-like family member J; CD85j; Ig-like transcript 2; ILT2; ILT-2; Immunoglobulin-like transcript 2; leucocyte Ig-like receptor B1; leukocyte immunoglobulin like receptor B1; leukocyte immunoglobulin-like receptor subfamily B member 1; leukocyte immunoglobulin-like receptor subfamily B member 1 soluble isoform; leukocyte immunoglobulin-like receptor subfamily B member 3-like; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1; LILRB1; LIR1; LIR-1; LOC100912456; MIR7; MIR-7; Monocyte/macrophage immunoglobulin-like receptor 7; myeloid inhibitory receptor 7; PIRB; PIR-B | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
10859 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Western Blot | |
1 mg/mL | |
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7 | |
Q8NHL6 | |
LILRB1 | |
Recombinant fragment corresponding to a region within amino acids 88 and 353 of Human LILRB1 | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |