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CDT1 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
145.00€ - 410.00€
Specifications
| Antigen | CDT1 |
|---|---|
| Concentration | 0.25 mg/mL |
| Applications | Western Blot, Immunocytochemistry, Immunofluorescence |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
16833004
|
Proteintech
14382-1-AP-20UL |
20 μL |
145.00€
20µL |
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|
16823004
|
Proteintech
14382-1-AP-150UL |
150 μL |
410.00€
150µL |
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Description
KMT2A is a histone methyltransferase that plays an essential role in early development and hematopoiesis. It is a catalytic subunit of the MLL1/MLL complex, a multiprotein complex that mediates both methylation of ′Lys-4′ of histone H3 (H3K4me) complex and acetylation of ′Lys-16′ of histone H4 (H4K16ac). In the MLL1/MLL complex, KMT2A specifically mediates H3K4me, a tag for epigenetic transcriptional activation. KMT2A has weak methyltransferase activity by itself, and requires other components of the MLL1/MLL complex to obtain full methyltransferase activity. It has no activity toward histone H3 phosphorylated on ′Thr-3′, less activity toward H3 dimethylated on ′Arg-8′ or ′Lys-9′, and has higher activity toward H3 acetylated on ′Lys-9′. Required for transcriptional activation of HOXA9 and promotes PPP1R15A-induced apoptosis.Specifications
| CDT1 | |
| Western Blot, Immunocytochemistry, Immunofluorescence | |
| Unconjugated | |
| Rabbit | |
| Human | |
| Q9H211 | |
| 81620 | |
| CDT1 Fusion Protein Ag5810 | |
| Primary | |
| -20°C | |
| CDT1 |
| 0.25 mg/mL | |
| Polyclonal | |
| Liquid | |
| RUO | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| CDT1, DNA replication factor Cdt1, Double parked homolog, DUP, RIS2 | |
| CDT1 | |
| IgG | |
| Antigen Affinity Chromatography | |
| Antibody |
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