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Cimetidine, 98+%

Product Code. 15475129
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Product Code. 15475129 Supplier Thermo Scientific Alfa Aesar Supplier No. J62825.14
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Description

H2 histamine receptor antagonist | CAS: 51481-61-9 | C10H16N6S | 252.34 g/mol

Widely used H2 histamine antagonist which has more recently been described as an inverse agonist. Also a potent I1 imidazoline binding site ligand. It displays antitumor and immunomodulatory activity. Cimetidine competitively inhibits histamine binding to histamine H2 receptors, and suppresses the growth of several tumors, including gastrointestinal cancer. This compound is an anti-angiogenic agent and is an activator of Nischarin. Competitive histamine H2-receptor antagonist which inhibits gastric acid secretion and reduces pepsin output

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Widely used H2 histamine antagonist which has more recently been described as an inverse agonist. Also a potent I1 imidazoline binding site ligand. It displays antitumor and immunomodulatory activity. Cimetidine competitively inhibits histamine binding to histamine H2 receptors, and suppresses the growth of several tumors, including gastrointestinal cancer. This compound is an anti-angiogenic agent and is an activator of Nischarin. Competitive histamine H2-receptor antagonist which inhibits gastric acid secretion and reduces pepsin output

Solubility
Soluble to 50 mM in water and to 100 mM in DMSO, solubility in HCl (almost transparency).

Notes
Store away from heat and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 51481-61-9
Molecular Formula C10H16N6S
Molecular Weight (g/mol) 252.34
MDL Number MFCD00133296
InChI Key AQIXAKUUQRKLND-UHFFFAOYSA-N
Synonym cimetidine, tagamet, tametin, eureceptor, cimetag, acinil, tratul, cimetidina, dyspamet, ulcedine
PubChem CID 2756
ChEBI CHEBI:3699
IUPAC Name 1-cyano-2-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine
SMILES CC1=C(N=CN1)CSCCNC(=NC)NC#N

Specifications

Melting Point 139°C to 144°C
Color White
Quantity 25 g
Merck Index 14,2279
Solubility Information Soluble to 50 mM in water and to 100 mM in DMSO,solubility in HCl (almost transparency).
Formula Weight 252.34
Percent Purity ≥98%
Physical Form Powder
Chemical Name or Material Cimetidine

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