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Description
During the proliferation phase of a bacterium, a segmental twisting and untwisting of the chromosomes takes place. An enzyme called DNA gyrase plays a decisive part in this process. Ciprofloxacin inhibits this DNA gyrase in a way that arrests the bacterial metabolism, since vital information can no longer be read from the bacterial chromosome. Ultimately, it affects DNA replication and cell division.
Ciprofloxacin is most commonly used to treat infections of the skin, bone, sinus, lung, abdomen, and bladder. It can also be used to treat some sexually transmitted infections. Additionally, ciprofloxacin can be used after exposure to inhalation of anthrax to reduce the chance of developing an infection.
Specifications
Specifications
| Physical Form | Powder |
| pH | 3.7 (2% aq. soln.) (literature) |
| Melting Point | 313°C to 322°C |
| Quantity | 5 g |
| Solubility Information | Stock solutions can be prepared in water or 0.1M NaOH (1-10mg/mL). |
| Formula Weight | 367.8g/mol (anhyd.) |
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