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Invitrogen™ CLOCK Polyclonal Antibody
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Product Code. 11503591
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Quantity:
200 μL
Unit Size:
200µL
Product Code. Quantity unitSize
11503591 200 μL 200µL
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Product Code. 11503591

Brand: Invitrogen™ PA1520

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This item is not returnable. View return policy

Description

Rabbit Polyclonal Antibody

PA1-520 detects CLOCK from human, mouse, rat and hamster tissues. PA1-520 has been successfully used in Western blot, ICC/IF and immunohistochemistry procedures. By Western blot, this antibody detects an ~100 kDa protein representing CLOCK from rat brain homogenate. Immunohistochemical staining of CLOCK in hamster brain with PA1-520 results in the staining of the superchiasmatic nucleus. PA1-520 immunizing peptide corresponds to amino acid residues 11-30 of mouse CLOCK. This sequence is completely conserved between mouse and human CLOCK. PA1-520 immunizing peptide (Cat. # PEP-072) is available for use in neutralization and control experiments.

This gene encodes a protein that belongs to the basic helix-loop-helix (bHLH) family of transcription factors. Polymorphisms within the encoded protein have been associated with circadian rhythm sleep disorders. A similar protein in mice is a circadian regulator that acts as a transcription factor and forms a heterodimer with aryl hydrocarbon receptor nuclear translocator-like to activate transcription of mouse period 1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CLOCK
Applications Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1mg/mL BSA and 0.05% sodium azide
Gene CLOCK
Gene Accession No. O08785, O15516, Q9WVS9
Gene Alias 5330400M04Rik; bHLHe8; circadian locomoter output cycles kaput; circadian locomoter output cycles kaput protein; circadian locomoter output cycles protein kaput; circadian locomotor output cycles kaput; class E basic helix-loop-helix protein 8; CLOCK; clock circadian regulator; clock homolog; hCLOCK; I79_020252; KAT13D; KIAA0334; mCLOCK; rCLOCK
Gene Symbols CLOCK
Host Species Rabbit
Immunogen Synthetic Peptide: S(11) S I V D R D D S S I F D G L V E E D D(30) C.
Purification Method Antigen affinity chromatography
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100770092, 12753, 60447, 9575
Target Species Human, Mouse, Rat, Hamster
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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