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Ambion™ Custom Silencer™ siRNA
Beschreibung
Spezifikation
Spezifikation
| Content And Storage | Room temperature |
| Description | Custom siRNA, 20nmol, FAM Purity, RNAi is the best Way to Effectively Knock Down Gene Expression to Study Protein Function in a Wide Range of Cell Types, Use our GeneAssist Custom siRNA Builder to Design and Order a Custom siRNA |
| For Use With (Application) | RNAi, epigenetics and non-coding RNA research, RNAi, siRNA |
| Product Type | Custom siRNA |
| Purity | FAM |
| Quantity | 20 nmol |
Frequently Asked Questions (FAQs)
For any RNAi duplex (miRNA or siRNA) there is a possibility that adding a modification will affect how the antisense strand interacts with RISC and aligns with its mRNA target, thus impacting functionality. For that reason, we recommend that you label the 5' end of the sense strand for siRNA (or passenger strand for miRNA). Since the 5' end of the antisense (guide strand) is what gets recognized by RISC, it is best to add the fluorescent modification to the end of the duplex on the strand that does not interact with RISC. You can also test a labeled vs. non-labeled RNAi duplex to determine if the modification is affecting the siRNA or miRNA functionality.
For Research Use Only. Not for use in diagnostic procedures.
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