missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ TSLP Recombinant Rabbit Monoclonal Antibody (2M5O9)
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA558157
This item is not returnable.
View return policy
Description
Immunogen sequence: YDFTNCDFEK IKAAYLSTIS KDLITYMSGT KSTEFNNTVS CSNRPHCLTE IQSLTFNPTA GCASLAKEMF AMKTKAALAI WCPGYSETQI NATQAMKKRR KRKVTTNKCL EQVSQLQGLW RRFNRPLLKQ Q.
TSLP is a 159 amino acid four helix-bundle hemopoietic cytokine that signals through a heterodimeric receptor complex consisting of the human TSLP receptor and the IL-7R alpha-chain. It impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes, enhances the maturation of CD11c (+) dendritic cells, naive CD4 (+), and CD8 (+) T cells into proallergic effectors, and primes dendritic cells to produce large amounts of IL-12 after CD40 ligand stimulation. TSLP influences the regulation of the positive selection of regulatory T cells and maintenance of peripheral CD4 (+) T cell homeostasis. It induces allergic inflammation by directly activating mast cells and may be involved in the pathophysiology of inflammatory arthritis. It is expressed in heart, liver and prostate.
Specifications
| TSLP | |
| Recombinant Monoclonal | |
| 1.15 mg/mL | |
| PBS with 0.05% BSA, 50% glycerol and 0.09% sodium azide; pH 7.3 | |
| Q9JIE6 | |
| TSLP | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 29-159 of human TSLP (NP_149024.1). | |
| 20 μL | |
| Primary | |
| Mouse | |
| Antibody | |
| IgG |
| ELISA, Immunocytochemistry | |
| 2M5O9 | |
| Unconjugated | |
| TSLP | |
| Thymic stroma-derived lymphopoietin; thymic stromal lymphopoietin; TSLP | |
| Rabbit | |
| Protein A | |
| RUO | |
| 53603 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction