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Cytochrome c Antibody (CYCS/1010), Novus Biologicals™
Mouse Monoclonal Antibody
265.00€ - 474.00€
Especificaciones
| Antigen | Cytochrome c |
|---|---|
| Clone | CYCS/1010 |
| Concentration | 0.2mg/mL |
| Dilution | Western Blot 0.5 - 1.0 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.25 - 0.5 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml |
| Applications | Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence |
| Código de producto | Marca | Quantity | Precio | Cantidad y disponibilidad | |||||
|---|---|---|---|---|---|---|---|---|---|
| Código de producto | Marca | Quantity | Precio | Cantidad y disponibilidad | |||||
|
18108308
|
Novus Biologicals
NBP2-44446-0.02MG |
0.02 mg |
265.00€
0.02mg |
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|
18171878
|
Novus Biologicals
NBP2-44446-0.1MG |
0.1 mg |
474.00€
0.10mg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Descripción
Ensure accurate, reproducible results in Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Cytochrome c Monoclonal specifically detects Cytochrome c in Human, Rat samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin.Especificaciones
| Cytochrome c | |
| 0.2mg/mL | |
| Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence | |
| Unconjugated | |
| Mouse | |
| Apoptosis, Cellular Markers, Cholesterol Metabolism, Core ESC Like Genes, Lipid and Metabolism, Mitochondrial Markers, Stem Cell Markers | |
| 1.0mM PBS and 0.05% BSA with 0.05% Sodium Azide | |
| CYCHCS, cytochrome c, cytochrome c, somatic, THC4 | |
| CYCS | |
| IgG2b κ | |
| Protein A or G purified | |
| Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This MAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached). |
| CYCS/1010 | |
| Western Blot 0.5 - 1.0 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.25 - 0.5 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml | |
| Monoclonal | |
| Purified | |
| RUO | |
| Human, Rat | |
| P99999 | |
| 54205 | |
| Recombinant full-length human CYCS protein | |
| Primary | |
| Store at 4C. | |
| 15 kDa |
For Research Use Only
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