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Decorin Polyclonal Antibody, Invitrogen™

Sheep Polyclonal Antibody

Brand:  Invitrogen PA185833

Product Code. 11593711

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Description

Description

Sheep anti human decorin antibody recognizes the C-terminal region of human bone proteoglycan II, also known as decorin, PG-S2 or PG40.

Decorin is a member of the small, leucine-rich proteoglycan (SLRP) family along with biglycan. Found in the interterritorial region of cartilage, decorin interacts with collagen and other matrix proteins to regulate the cartilaginous matrix. It has been shown to interact with fibronectin, thrombospondin, C1q, epidermal growth factor receptor (EGFR), and TGF-b. It is believed that decorin also plays a role in the cell cycle of chondrocytes. The decorin neoepitope fragment has a sequence of PKTLQE, and is generated by MMP-3 or ADAMTS-4 cleavage at Glu154-Leu155 of decorin core protein.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Decorin
Polyclonal
Unconjugated
DCN
Bone proteoglycan II; CSCD; DC; Dcn; DCN protein; DCN1C; Decorin; decorin isoform a preproprotein; Dermatan sulfate proteoglycan-II; dermatan sulfate proteoglycan-II (decorin); dermatan sulphate proteoglycans II; Dermatan sulphate proteoglycans II (DSPG2); DSPG; DSPG2; mDcn; PG40; PGII; PGS2; PG-S2; proteoglycan core protein; proteoglycan core protein; binds type I collagen fibers and TGF-beta; decoron; similar to bone proteoglycan II; similar to decorin; SLRR1B; Small leucine rich protein 1B; small leucine-rich protein 1B; unnamed protein product
Sheep
Protein G
RUO
1634, 280760, 417892
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
ELISA, Western Blot
5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P07585, P21793, P28675
DCN
Synthetic peptide, KLH conjugated, corresponding to residues C(316) V Y V R S A I Q L G N Y K(329) of Bone Proteoglycan II Precursor.
1 mL
Primary
Bovine, Chicken, Human
Antibody
IgG
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