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Deoxycholic acid, sodium salt, 99%, extra pure

Product Code. 10562904 Shop All Thermo Scientific Chemicals Products
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Product Code. 10562904 Supplier Thermo Scientific Acros Supplier No. 218595000
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Description

Deoxycholic acid, sodium salt, CAS # 302-95-4, also designed as sodium deoxycholate, is a biological anionic bile acid detergent that is especially useful for disrupting and dissociating protein interactions. | CAS: 302-95-4 | C24H39NaO4 | 414.56 g/mol

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • The deoxycholic acid sodium salt is a bile acid choleretic and anionic detergent that allows the solubilization of fats for intestinal absorption
  • The compound is an intermediate in the production of corticosteroids
  • In animal models it has been shown that this compound can promote tyrosine phosphorylation of β-catenin and its translocation to the nucleus, promoting the activation of β-catenin signaling


Applications

  • Deoxycholic acid is mainly useful for the extraction of membrane receptors, other plasma membrane proteins, nuclei isolation, solubilization and isolation of fats, and some components of biological membranes (in an active state)
  • It has been used for chemical applications, mainly for the elution or regeneration of specific types of affinity columns. Furthermore, this compound can be used to prevent non-specific binding in affinity chromatography.
  • It has been applied in the preparation of protein extracts for immunoblotting and immunoprecipitation of radiolabeled proteins
  • Deoxycholic acid, sodium salt is also recommended for stripping endotoxins
TRUSTED_SUSTAINABILITY

Identificatori chimici

CAS 302-95-4
Molecular Formula C24H39NaO4
Molecular Weight (g/mol) 414.56
MDL Number MFCD00064139
InChI Key FHHPUSMSKHSNKW-SMOYURAASA-M
Synonym sodium deoxycholate
PubChem CID 91810855
SMILES [Na+].[H][C@@]12CC[C@H]([C@H](C)CCC([O-])=O)[C@@]1(C)[C@@H](O)C[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@H](O)CC[C@]12C

Specifica

Color Cream to White
pH 7.5 to 10 (5% aq. soln.)
Loss on Drying 5% max. (2 g, 105°C, 4 hrs)
Infrared Spectrum Authentic
Assay Percent Range 99%
Packaging Glass bottle
Quantity 500 g
Beilstein 10, III, 1642
Merck Index 14, 2899
Specific Rotation +42° to +46° (20°C, 589 nm) (c=2, water)
IUPAC Name sodium (4R)-4-[(1R,3aS,3bR,5aR,7R,9aS,9bS,11S,11aR)-7,11-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoate
Formula Weight 414.58
Percent Purity 98.5 to 102% (on dry substance)
Grade Extra Pure
Physical Form Crystalline Powder
Chemical Name or Material Deoxycholic acid, sodium salt
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Sicurezza e movimentazione

compliance-icons
Identificativo prodotto
  • Deoxycholic acid, sodium salt
 Avvertenza
  • Warning
 Categoria di pericolo
  • Acute toxicity Category 4
  • LONG-TERM AQUATIC HAZARD Chronic 3
 Indicazioni di pericolo
  • H412-Harmful to aquatic life with long lasting effects.
  • H302-Harmful if swallowed.
 Consigli di prudenza
  • P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P264-Wash face, hands and any thoroughly after handling.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P312-Call a POISON CENTER/doctor/if you feel unwell.
SDS

RUO – Research Use Only

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