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Dextran Sulfate Sodium Salt, Colitis Grade (36,000 to 50,000), MP Biomedicals™
Tous les produits MP Biomedicals ProduitsDescription
Induces severe colitis (inflammatory bowel disease) in laboratory animals
Dextran sulfate sodium salt, or DSS, is a synthetic sulfated branched polysaccharide derivative of dextran that has multiple uses in biomedical and clinical research. One important property of DSS is to trigger colitis in mice and rats when administered in drinking water. DSS binds to medium-chain-length fatty acids in the colon and induces intestinal inflammation. Colitis-grade DSS (MW = 36,000 to 50,000) from MP Bio is one of the most widely used products based on peer reviewed scientific publications.
- Induces severe colitis (inflammatory bowel disease)
- Highest sulfur content – 19%
- Highest chirality - +104° of specific rotation
- Lowest pH – 6.2 at 1% solution
Spécification
Spécification
| Chemical Name or Material | Dextran Sulfate Sodium Salt |
| Color | White |
| pH | 5 to 7.11 (1% aqueous solution) |
| CAS | 9011-18-1 |
| Physical Form | Powder |
| Boiling Point | 310°C |
| Melting Point | 92°C |
| Molecular Formula | (C6H7O5)m(C6H7O5)n |
| MDL Number | MFCD00081551 |
| Solubility Information | Soluble in water |
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Sécurité et traitement
- Dextran Sodium Sulfate, MW = 36,000-50,000
- Warning
- Skin corrosion/irritation Category 2
- Serious eye damage/eye irritation Category 2
- Specific target organ toxicity Category 3
- H315-Causes skin irritation.
- H319-Causes serious eye irritation.
- H335-May cause respiratory irritation.
- P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P321-Specific treatment (see on this label).
- P405-Store locked up.
- P501-Dispose of contents/container to in accordance with all local, regional,national and international regulations.
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use.
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