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Dextran Sulfate Sodium Salt, Colitis Grade (36,000 to 50,000), MP Biomedicals™

Code produit 11454352 Tous les produits MP Biomedicals Produits
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Code produit 11454352 Fournisseur MP Biomedicals Code fournisseur 0216011090

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Les retours ne sont pas autorisés pour ce produit. Afficher la politique du retour.

Induces severe colitis (inflammatory bowel disease) in laboratory animals

Dextran sulfate sodium salt, or DSS, is a synthetic sulfated branched polysaccharide derivative of dextran that has multiple uses in biomedical and clinical research. One important property of DSS is to trigger colitis in mice and rats when administered in drinking water. DSS binds to medium-chain-length fatty acids in the colon and induces intestinal inflammation. Colitis-grade DSS (MW = 36,000 to 50,000) from MP Bio is one of the most widely used products based on peer reviewed scientific publications.

  • Induces severe colitis (inflammatory bowel disease)
  • Highest sulfur content – 19%
  • Highest chirality - +104° of specific rotation
  • Lowest pH – 6.2 at 1% solution
TRUSTED_SUSTAINABILITY

Spécification

Chemical Name or Material Dextran Sulfate Sodium Salt
Color White
pH 5 to 7.11 (1% aqueous solution)
CAS 9011-18-1
Physical Form Powder
Boiling Point 310°C
Melting Point 92°C
Molecular Formula (C6H7O5)m(C6H7O5)n
MDL Number MFCD00081551
Solubility Information Soluble in water
Quantity 500 g
InChI Key BLFLLBZGZJTVJG-UHFFFAOYSA-N
SMILES *-OC[C@H]1O[C@H](OC[C@H]2O[C@H](-*)[C@H](O[*])[C@@H](O[*])[C@@H]2O[*])[C@H](O[*])[C@@H](O-*)[C@@H]1O[*]
IUPAC Name Dextran sulfate sodium salt
Molecular Weight (g/mol) 40,000
For Use With (Application) Used for inducing ulcerative colitis in animals and extensively to study colon cancer developing in relation to colonic inflammation
Grade Colitis Grade
Moisture <10%
Packaging Plastic Container
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Identifiant produit
  • Dextran Sodium Sulfate, MW = 36,000-50,000
Mention d'avertissement
  • Warning
Catégorie de danger
  • Skin corrosion/irritation Category 2
  • Serious eye damage/eye irritation Category 2
  • Specific target organ toxicity Category 3
Mention de danger
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
Conseils de prudence
  • P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P321-Specific treatment (see on this label).
  • P405-Store locked up.
  • P501-Dispose of contents/container to in accordance with all local, regional,national and international regulations.

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use.

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