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Invitrogen™ DNA Ligase III Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5102510
This item is not returnable.
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Description
Antibody detects endogenous levels of total DNA Ligase III.
There are four distinct ligase proteins found in mammalian cells. The activity of these DNA ligases is required for the joining of DNA strand breaks that occur during DNA replication, repair and recombination. DNA Ligase III gene product migrates as a 100 kDa (a-form) protein in somatic tissues, is ubiquitously expressed and complexes with XRCC-1 and a 97 kDa (beta form) protein that is found in testis. DNA Ligase III is involved in rejoining DNA single-strand breaks and in the base excision repair pathway.
Specifications
| DNA Ligase III | |
| Polyclonal | |
| Unconjugated | |
| LIG3 | |
| D11Wsu78e; DNA ligase (ATP) 3; DNA ligase 3; DNA ligase III; hypothetical protein; LIG2; LIG3; ligase II, DNA, ATP-dependent; ligase III, DNA, ATP-dependent; polydeoxyribonucleotide synthase [ATP] 3; Unknown (protein for MGC:134139) | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 16882, 303369, 3980 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P49916, P97386 | |
| LIG3 | |
| A synthesized peptide derived from human LIG3(Accession P49916), corresponding to amino acid residues D641-D691. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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