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Invitrogen™ EHD1 Polyclonal Antibody
Goat Polyclonal Antibody
Brand: Invitrogen™ PA5142121
This item is not returnable.
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Description
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
EHD1 acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. EHD1 also plays a role in myoblast fusion and is recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth. Further, EHD1 belongs to a highly conserved gene family encoding EPS15 homology (EH) domain-containing proteins. The protein-binding EH domain was first noted in EPS15, a substrate for the epidermal growth factor receptor. The EH domain has been shown to be an important motif in proteins involved in protein-protein interactions and in intracellular sorting. The EHD1 protein is thought to play a role in the endocytosis of IGF1 receptors. Alternatively spliced transcript variants have been found for the EHD1 gene.
Specifications
| EHD1 | |
| Polyclonal | |
| Unconjugated | |
| EHD1 | |
| AA409636; CDABP0131; EH domain containing 1; EH domain-containing protein 1; Ehd1; EH-domain containing 1; H-PAST; HPAST1; mPAST1; PAST; PAST homolog 1; PAST1; RGD1306960; RME-1; testilin | |
| Goat | |
| Ammonium sulfate precipitation | |
| RUO | |
| 10938, 13660 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 0.5 mg/mL | |
| TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
| Q9H4M9, Q9WVK4 | |
| EHD1 | |
| Peptide with sequence FSWVSKDARRKKEPC (aa 2-15). | |
| 100 μg | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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