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ERCC1 Monoclonal Antibody (OTI5E2), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA805666
This item is not returnable.
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Description
The mammalian ERCC1 (Excision Repair Cross Complementing) polypeptide is required for nucleotide excision repair (NER) of damaged DNA and is homologous to Saccharomyces cerevisiae RAD10, which functions in repair and mitotic intrachromosomal recombination. NER mechanism involves dual incisions on both sides of the damage catalyzed by two nucleases. In mammalian cells XPG cleaves 3′ of the DNA lesion while the ERCC1-XPF complex makes the 5′ incision.Specifications
| ERCC1 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| P07992 | |
| ERCC1 | |
| Full length human recombit protein of human ERCC1 produced in HEK293T cell. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG2a |
| Immunohistochemistry (Paraffin), Western Blot | |
| OTI5E2 | |
| Unconjugated | |
| ERCC1 | |
| COFS4, RAD10, UV20 | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 2067 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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