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Gr-1 (Ly-6G/Ly-6C) Rat, anti-Mouse, Alexa Fluor 488, Clone: RB6-8C5, STEMCELL Technologies
Rat Monoclonal Antibody
Brand: Stemcell Technologies 60028AD
This item is not returnable.
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Description
- The RB6-8C5 antibody reacts with the structurally related murine Ly-6G (21 - 25 kDa) and Ly-6C (14 - 16 kDa) GPI-anchored proteins, which together comprise the granulocyte receptor-1 antigen (Gr-1)
- Gr-1 is expressed on monocytes, neutrophils, subsets of macrophages, plasmacytoid dendritic cells, and T cells
- Monocytes in the bone marrow transiently express Gr-1 during development and the expression level is strongly correlated with granulocyte differentiation and maturation
- In the periphery Gr-1 is found predominantly on neutrophils and is a useful marker for these cells
- Whereas the RB6-8C5 binds to both Ly-6G and Ly-6C, another commonly used anti-Gr-1 antibody, clone 1A8, binds specifically to Ly-6G
- This antibody clone has been verified for purity assessments of cells isolated with EasySep™ kits, including EasySep™ Mouse Neutrophil Enrichment Kit (Catalog #19762)
Specifications
| Gr-1 (Ly-6G/Ly-6C) | |
| Monoclonal | |
| Alexa Fluor 488 | |
| 100 μg | |
| Mouse | |
| Granulocytes and Subsets, Monocytes, Myeloid Cells |
| Immunoprecipitation, Western Blot, Flow Cytometry, Immunocytochemistry | |
| RB6-8C5 | |
| Rat | |
| Primary | |
| IgG2b κ |
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