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Epredia™ Lab Vision™ Granzyme B Ab-1, Mouse Monoclonal Antibody

Ensure accurate, reproducible results in immunohistochemistry experiments with Epredia™ Granzyme B Ab-1, Mouse Monoclonal Antibody.

144.84€ - 695.00€

Specifications

Antigen Granzyme B Ab-1
Clone GZB01
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Conjugate Unconjugated
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Products 5
Product Code Brand Form Quantity Price Quantity & Availability  
Product Code Brand Form Quantity Price Quantity & Availability  
12659136
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Epredia™
MS-1157-S1
Concentrated 500 μL
455.00€
500µL
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Estimated Shipment: 11-06-2024
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12639136
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Epredia™
MS-1157-S
Concentrated 1 mL
695.00€
1mL
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12649136
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Epredia™
MS-1157-S0
Concentrated 100 μL This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Technical Support team on 056 260 260 for assistance.
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12629136
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Epredia™
MS-1157-R7
Prediluted 7 mL This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Technical Support team on 056 260 260 for assistance.
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12619136
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Epredia™
MS-1157-RQ
Ready-to-Use 12 mL This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Technical Support team on 056 260 260 for assistance.
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Description

Description

Granzymes are neutral serine proteases, which are stored in specialized lytic granules of cytotoxic T lymphocytes (CTLs) and in natural killer (NK) cells. A number of granzymes (A to G) have been isolated and cloned from mouse CTLs and NK cells, however in man, fewer have been cloned and identified. One of these, human granzyme B, is involved in target cell apoptosis during lymphocyte-mediated cytotoxicity. Exocytosis of granzyme-containing granules in the cytoplasm of the target cell leads to the induction of DNA fragmentation and apoptosis.

Host Species: Mouse

Clone: GZB01

Isotype: IgG2a

Species Reactivity: Human. Others not known.

Epitope: N-terminal

Immunogen: Recombinant protein encoding the N-terminus of the mature granzyme B

Molecular Weight: 32 kDa

Positive Control: Hodgkin's lymphoma, Tonsil

Cellular Localization: Granular cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin only)

Specifications

Specifications

Granzyme B Ab-1
Immunohistochemistry (Paraffin)
Unconjugated
IVD
Recombinant protein encoding the N-terminus of the mature granzyme B
GZB01
Monoclonal
Mouse
Apoptosis
Primary
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