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GTF2IRD1 Monoclonal Antibody (OTI9A3), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA809948
This item is not returnable.
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Description
Williams-Beuren syndrome (WBS) is a developmental disorder caused by the hemizygous microdeletion on chromosome 7q11.23. WBS is an autosomal domit genetic condition that is characterized by physical, cognitive and behavioral traits. The physical traits associated with WBS include facial dysmorphology, vascular stenoses, growth deficiencies, dental anomalies and neurologic and musculoskeletal abnormalities. Mild retardation, a weakness in visual-spatial skills, anxiety and a short attention span are typical cognitive and behavioral traits of WBS patients. The WBSCR11 gene is located within the WBS deletion and may contribute to the developmental symptoms found in WBS because of a loss of the encoded transcription factor. WBSCR11 is also designated GRF2IRD1, GTF3, Cream1 and MusTRD1 in human and BEN in mouse, due to slight differences in gene structure. WBSCR11 is expressed in all adult tissues as several variants and has discrete spatial and temporal expression during embryogenesis.Specifications
| GTF2IRD1 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| BEN, CREAM1, GTF3, MUSTRD1, RBAP2, WBS, WBSCR11, WBSCR12, hMusTRD1alpha1 | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 9569 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Western Blot | |
| OTI9A3 | |
| Unconjugated | |
| GTF2IRD1 | |
| GTF2IRD1 | |
| Human recombit protein fragment corresponding to amino acids 400-540 of human GTF2IRD1 produced in E.coli. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
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