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Harmine, 98+%

Código de producto. 11359615
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Quantity:
250 mg
1 g
Tamaño de la unidad:
1g
250mg
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Código de producto. 11359615 Proveedor Thermo Scientific Alfa Aesar N.º de proveedor L19068.MD
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Descripción

CAS: 442-51-3 | C13H12N2O | 212.25 g/mol

Harmine, inhibits the Wnt signaling pathway in a cell-specific manner. Down-regulates inflammatory gene expression (TNF-α, IL-1β, iNOS). Reversibly inhibits MAO-A (monoamine oxidase A) but has no effect on MAO-B. Harmine is an inhibitor of Dyrk1A, Dyrk2 and Dyrk3.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Harmine, inhibits the Wnt signaling pathway in a cell-specific manner. Down-regulates inflammatory gene expression (TNF-α, IL-1β, iNOS). Reversibly inhibits MAO-A (monoamine oxidase A) but has no effect on MAO-B. Harmine is an inhibitor of Dyrk1A, Dyrk2 and Dyrk3.

Solubility
Soluble in DMSO (100 mM), DMF (∼1.5 mg/ml), ethanol (∼1.5 mg/ml), and PBS (pH 7.2, ∼0.25 mg/ml). Insoluble in water.

Notes
Keep container tightly closed in a dry and well-ventilated place. Keep away from oxidizing agents. Stable under recommended storage conditions.
TRUSTED_SUSTAINABILITY

Identificadores de productos químicos

CAS 442-51-3
Molecular Formula C13H12N2O
Molecular Weight (g/mol) 212.25
MDL Number MFCD00004958
InChI Key BXNJHAXVSOCGBA-UHFFFAOYSA-N
Synonym harmine, 7-methoxy-1-methyl-9h-pyrido 3,4-b indole, banisterine, leucoharmine, telepathine, yageine, yajeine, 7-methoxy-1-methyl-9h-beta-carboline, 9h-pyrido 3,4-b indole, 7-methoxy-1-methyl, banisterin
PubChem CID 5280953
ChEBI CHEBI:28121
IUPAC Name 7-methoxy-1-methyl-9H-pyrido[3,4-b]indole
SMILES COC1=CC2=C(C=C1)C1=C(N2)C(C)=NC=C1

Especificaciones

Melting Point 262°C to 266°C
Odor Odorless
Quantity 250 mg
Beilstein 178813
Merck Index 14,4616
Solubility Information Soluble in DMSO (100 mM),DMF (∽1.5mg/ml),ethanol (∽1.5mg/ml),and PBS (pH 7.2,∽0.25mg/ml). Insoluble in water.
Formula Weight 212.25
Percent Purity ≥98%
Chemical Name or Material Harmine

RUO – Research Use Only

Título del producto
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