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Cytiva HiTrap™ Capto™ MMC ImpRes Column

Product Code. 16360906 Shop All Cytiva Products
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Product Code. 16360906 Supplier Cytiva Supplier No. 29401108

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Description

Prepacked with a weak cation exchange multimodal resin for screening and small-scale purifications

  • The multimodal functionality of Capto MMC ImpRes offers a different selectivity compared to traditional ion exchange columns
  • Binds proteins at high or low ionic strength
  • Efficiently removes contaminants such as DNA, host cell proteins (HCP), leached protein A, and aggregates
  • An excellent choice for purification of MAbs and other biomolecules with high aggregate content.
  • Can typically be used in the initial polishing step in MAb purification processes, as well as for polishing of antibody fragments such as domain antibodies (DAbs)
  • High yields achieved through the high-resolution beads and selectivity of the ligand
  • Enables use of a platform approach to MAb process development
  • Displays a broad pH/salt operational window
  • Ideal for screening of selectivity, binding, and elution conditions, as well as for small scale purifications
TRUSTED_SUSTAINABILITY

Specifications

Description High-Resolution Polishing of Monoclonal Antibodies (MAbs) and Other Biomolecules
Matrix High-Flow Agarose
Flow Rate <4 mL/min
For Use With (Application) Multimodal Ion Exchange Chromatography
Ligand Type Multimodal Weak Cation Exchanger
Content And Storage Store at 4°C to 30°C in 20% Ethanol, 0.2 M Sodium Acetate
Binding Strength 60 to 90 mg MAb/mL
Max. Operating Pressure 5 bar (70 psi)
Column Type Pre-packed Column
Diameter (Metric) Inner Column 7 mm
Volume (Metric) 1 mL
pH 3 to 12
Quantity 1 Ea.
Length (Metric) 25 mm
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Safety and Handling

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Product Identifier
  • HiTrap Capto MMC ImpRes, 1 x 1 ml
 Signal Word
  • Warning
 Hazard Category
  • Flammable liquid Category 3
 Hazard Statement
  • H226-Flammable liquid and vapour.
 Precautionary Statement
  • P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
 Supplemental information
  • MIXTURE LIST-Contains : ethanol
  • UNKNOWN ACUTE-16.5 per cent of the mixture consists of component(s) of unknown acute toxicity.
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